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A shipmate of Crean's overheard him volunteering for the dangerous expedition and declared, "I didn't think you were crazy enough for a mad trip to the end of the world." Crean responded, "Haven't I been mad enough to come from the other end of the world?" Crean's willingness to volunteer reflected his self-confidence and belief in his own abilities

Electronic cigarette use intensity measurement challenges and regulatory implications

Hawaii's quit line is one of the programs funded by the 20 year old Tobacco Settlement

Conducted under actual use conditions over an 8-week observational period in 2022, our study investigated the ability of a novel e-vapor product (an electronic nicotine delivery system [ENDS], specifically, the P4M3 Generation 2.0 System, featuring nonrefillable, replaceable cartridges filled with nicotine-containing e-liquid) in helping adult smokers either reduce their cigarette consumption or completely transition away from cigarettes